TOPOLINK

A package to evaluate structural models using chemical crosslinking distance constraints.

Institute of Chemistry
University of Campinas

TopoLink:
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Usage
Tools
XLFF
XL Statistics
See also:
Dalton MS lab
SIM-XL
G-score
LovoAlign
Packmol
MDLovoFit
Group software page
The TANGO project
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XL Statistics

Here, we present general statistics that may be useful to guide chemical-crosslinking experiments and structural modeling. The data present consists on the evaluation of the possible crosslinks of the proteins of the CATH non-homologous protein database, evaluated with TopoLink.

The following data can be explored, as a function of protein type (all/alpha/beta), sequence length, and linker type:

Given a linker and sequence length, how many cross-links should I expect for each pair or residues? [click here]
Given a linker, how many cross-links should I expect as function of sequence length? [click here]